Fig. 3
From: Analysis of the impact of pluronic acid on the thermal stability and infectivity of AAV6.2FF
The effect of temperature on AAV6.2FF particle stability in different buffer formulations. Aliquots of 1x109 vg of AAV6.2FF-ffLuc formulated PBS or PBS supplemented with 0.001% PF-68 were exposed to a range of temperatures and durations. Following treatment, viral DNA was extracted and quantified by qPCR. The conditions tested were as follows: A -20℃, B 4℃, C 21℃, D 37℃, or E 55℃. A two-way ANOVA test was performed between the two buffer formulations in all exposure and treatment conditions. ns (not significant), * P ≤ 0.05, and **** P ≤ 0.0001