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Fig. 4 | BMC Biotechnology

Fig. 4

From: Research on the targeted improvement of the yield of a new VB12-producing strain, Ensifer adhaerens S305, based on genomic and transcriptomic analysis

Fig. 4

Enrichment analysis of significantly differentially expressed genes between the S305 strain and Casida A strain. A, B, C, D Volcano map of enriched genes with significant transcriptional differences between the S305 and Casida A strains during four cultivation periods (A-12 h, B-24 h, C-48 h, and D-72 h) under the same culture conditions. The blue dots represent downregulated genes, and the red dots represent upregulated genes (Padjust < 0.05, multiple change ≥ 2). E KEGG pathway enrichment analysis of genes with significant differences in expression in the S305 strain compared to the Casida A strain. P value < 0.001 is labelled as ***, P value < 0.01 is labelled as **, and P value < 0.05 is labelled as *. The colour gradient on the right side represents the P value. F The number of genes in metabolic pathways with significant differences in gene expression in the S305 strain

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