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Table 2 Effects of disrupting mtpA gene on organic acid production by A. carbonarius in shake flask fermentation

From: Disruption of a putative mitochondrial oxaloacetate shuttle protein in Aspergillus carbonarius results in secretion of malic acid at the expense of citric acid production

Strains/Titer (g/L)

Glucose consumption

Citric acid

Malic acid

WT

31.0 ± 1.27

2.6 ± 0.54

n.d.

mtpA-1

29.2 ± 7.83

1.6 ± 0.53

0.35 ± 0.19

  1. (Note: Cultivations were performed in triplicates, showing standard error of the mean, n.d. – non-detectable level in HPLC)
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BMC Biotechnology

ISSN: 1472-6750

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