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Table 4 IC50 of each parent and plasmid addition strain and percent differences of tolerance relative to the parent strain

From: Characterizing active transportation mechanisms for free fatty acids and antibiotics in Synechocystis sp. PCC 6803

Treatment

 

SD100

SD100 pacrA

SD100 pKan

SD100 pacrB

SD100 pSpec

 Amp

IC50

955.2 ± 256

1315 ± 77 (ns)

1151 ± 82 (ns)

1109 ± 123 (ns)

658.6 ± 88.3

% diff from SD100

0%

27%

20%

16%

−31%

 Cm

IC50

2.290 ± 0.401

1.444 ± 0.114

1.390 ± 0.186

1.976 ± 0.734 (ns)

1.653 ± 0.205 (ns)

% diff from SD100

0%

−59%

−39%

−14%

−28%

 Ery

IC50

0.358 ± 0.081 μg/mL

0.080 ± 0.003

0.072 ± 0.007

0.138 ± 0.080 (ns)

0.079 ± 0.005

% diff from SD100

0%

−77%

− 79%

−61%

−78%

Treatment

 

SD277

SD277 pacrA

SD277 pKan

SD277 pacrB

SD277 pSpec

 Amp

IC50

1570 ± 170 μg/mL

1117 ± 21 μg/mL

76.67 ± 28.5 μg/mL

118.2 ± 8.7 μg/mL

412.6 ± 34.8 μg/mL

% diff from SD277

0%

−29%

−95%

−92%

−74%

 Cm

IC50

4.749 ± 1.043 μg/mL

1.833 ± 0.390 μg/mL

1.793 ± 0.430 μg/mL

1.984 ± 0.527 μg/mL

2.96 ± 0.4 μg/mL

% diff from SD277

0%

−61%

− 62%

−58%

−38%

 Ery

IC50

0.427 ± 0.249 μg/mL

0.091 ± 0.034 μg/mL

0.149 ± 0.016 μg/mL

0.080 ± 0.008 μg/mL

0.055 ± 0.004 μg/mL

% diff from SD277

0%

−79%

−65%

−81%

−87%

  1. The basis for the comparison in this table were the parent strains, either SD100 or SD277, featured in the third column. Each derivative strain is significantly different from the parent strain unless otherwise noted with “(ns)”