HUGO subfamily | Sánchez-Fernández subfamilya | ABCISSE familyb,c | ABCISSE subfamilyb,c | TC subfamilyd | Domain organization | Taxa |
---|---|---|---|---|---|---|
ABCA | ABC1 homologue (AOH) | Drug and antibiotic resistance (DRA) | ABCA | Cholesterol/phospholipid/retinal flippase (CPR) | (TMD-NBD)2 | eukaryotes (not yeast) |
ABC2 homologue (ATH) | TMD-NBD | eukaryotes | ||||
ABCB | Multidrug resistance (MDR) | Drug, peptides and lipid export (DPL) | p-glycoprotein (p-GP) | MDR | (TMD-NBD)2 | prokaryotes and eukaryotes |
Transporter associated with antigen processing (TAP) | TAP and multidrug resistance-like protein (MDL) | TAP and mitochondrial peptide exporter (MPE) | TMD-NBD | eukaryotes | ||
ABC transporter of the mitochondria (ATM) | Heavy metal tolerance (HMT) | HMT | TMD-NBD | eukaryotes | ||
- | Lipid A-like exporter, putative (LLP) | - | TMD-NBD | prokaryotes and plants | ||
ABCC | Multidrug resistance associated protein (MRP) | Organic anion conjugates and drug export (OAD) | MRP | Conjugate transporter (CT) | (TMD-NBD)2 | eukaryotes |
ABCD | Peroxisomal membrane protein (PMP) | Fatty acid export (FAE) | - | Peroxisomal fatty acyl-CoA transporter (P-FAT) | TMD-NBD; (TMD-NBD)2 | bacteria and eukaryotes |
ABCE | RNase L inhibitor (RLI) | RNase L inhibitor (RLI) | - | - | NBD-NBD | archaea and eukaryotes |
ABCF | General control non-repressible (GCN) | Antibiotic resistance and translation regulation (ART) | Gene expression regulation (REG) | - | NBD-NBD | bacteria and eukaryotes |
ABCG | White-brown complex homologue (WBC) | Eye pigment precursors and drugs (EPD) | WHITE | Eye pigment precursor transporter (EPP) | NBD-TMD | bacteria and eukaryotes |
Pleiotropic drug resistance (PDR) | PDR | PDR | (NBD-TMD)2 | plants and fungi | ||
ABCH | - | Drug resistance, bacteriocin and lantibiotic immunity (DRI) | YHIH | Â | NBD-TMD | prokaryotes, slime moulds, echinoderms, insects and fish |