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Table 2 Regulators of p53 and Mdm2 identified by subscreening of the Medaka cDNA library. The table shows the number of the clone in the library, the identification number of the Ensembl database (Ensmble ID), the name of the gene, further details about the protein and its activity within the p53/Mdm2 circuit

From: Expression screening using a Medaka cDNA library identifies evolutionarily conserved regulators of the p53/Mdm2 pathway

Clone number

Ensembl ID

Gene name

 

Activity towards p53 and Mdm2

2.2 B6

not annotated

unknown

 

p53 abundance was increased

5.3D G3

ENSORLG00000007935

q3v605_oryla

Hoxc8a protein

p53 abundance was increased

5.3D G10

ENSORLG00000008784

galntl1

UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosa-minyltransferase-like 1

p53 and Mdm2 abundance were increased,

6.3 H5

ENSORLG00000003540

fubp1

far upstream element-binding protein 1

p53 abundance was decreased, Mdm2 abundance was increased

8.3D G10

ENSORLG00000006197

rbm15

RNA binding motif protein 15

p53 abundance was decreased, Mdm2 abundance was increased

9.1 H11

ENSORLG00000001826

trim25

Tripartite motif-containing protein 25

p53 and Mdm2 abundance were increased

10.4 B10

ENSORLG00000009742

bhlhe23

Basic helix-loop-helix family member e23

p53 abundance was increased

10.4 B12

ENSORLG00000009430

srsf4

Serine/arginine-rich splicing factor 4

p53 abundance was increased

15.1 F10

FOE002-P00040-DPE-F_A21

unknown

 

p53 abundance was decreased, Mdm2 abundance was increased

15.2C F9

not annotated

unknown

 

p53 abundance was decreased, Mdm2 abundance was increased

15.3 G5

ENSORLG00000016835

gns

Glucosamine (N-acetyl)-6-sulfatase

p53 and Mdm2 abundance were increased

15.4 C4

ENSORLG00000004985

mex3c

Mex-3 homolog C

p53 abundance was increased

18.2 F5

ENSORLG00000000208

c1orf144

C1-open reading frame 144 (PM20, PM21)

p53 abundance was increased

29.3 F1

ENSORLG00000004520

hsd1 1b 1 l

Hydroxysteroid (1 l-beta) dehydrogenase 1-like

p53 and Mdm2 abundance were increased

36.4 B D5

not annotated

unknown

 

p53 and Mdm2 abundance were increased

36.4 B D6

not annotated

unknown

 

Mdm2 abundance was increased

45.1 B2

ENSORLG00000001401

fam83f

Family with sequence similarity 83, member F

p53 abundance was increased