Table 1 Summary of the screening of a Medaka cDNA library for evolutionarily conserved regulators of p53 and Mdm2. The table shows the number of hits and their activity on the abundance of p53and/or Mdm2

p53 abundance is decreased

6

p53 abundance is increased

38

Mdm2 abundance is decreased

3

Mdm2 abundance is increased

11

p53 and Mdm2 abundance is decreased

1

p53 and Mdm2abundance is increased

43

p53 abundance is increased, Mdm2 abundance is decreased

1

p53 abundance is decreased, Mdm2 abundance is increased

3

Total

106