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Table 2 Comparison of Q-plexâ„¢ technology to traditional ELISA assays

From: Simultaneous multi-analyte urinary protein assay for bladder cancer detection

 

Q-plexâ„¢ array

Commercial ELISA assay

 

Cancer

Benign

Cancer

Benign

IL8 (pg/ml)

  

Median

127.7

2.2

100.8

144.3

(Min, Max)

(0.4, 5,087.5)

(0.5, 185.3)

(0, 4,355.3)

(0, 506.3)

Mean ± SD*

423.6 ± 931.2

14.6 ± 40.9

276.8 ± 768.9

180.0 ± 138.2

MMP9 (pg/ml)

  

Median

268,688

248,730.5

2,833.2

545.3

(Min, Max)

(176,103.9, 3,783,990.1)

(162,655.6, 867,918.5)

(0, 12,988.9)

(0, 7,146)

Mean + SD

469,075.4 ± 655,960.4

320,746.6 ± 171,092.6

5,236.0 ± 4,144.5

876.5 ± 1,353.0

VEGFA (pg/ml)

  

Median

12,599.4

12,677.5

143.6

19.5

(Min, Max)

(2,093.3, 498,114.9)

(810.1, 262,356.7)

(1.1, 9,874.1)

(0, 184.2)

Mean + SD

33,483.5 ± 88,403.7

20,690.5 ± 39,702.7

1061.6 ± 2132.9

36.2 ± 47.4

  1. *, p < 0.05 comparing cancer cohort to benign cohort for both Q-Plex™ Array and Commercial ELISA Assay.