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Table 2 Performance of our method in detecting markers

From: A method for cell type marker discovery by high-throughput gene expression analysis of mixed cell populations

Cell line

Range

Markers

Top5

Top10

Top20

Expected top20

Correlation of 20th

K562

0.1% to 3%

486

4

7

13

0 to 1 (0.523)

0.81

HL60

5% to 13%

1237

3

5

5

1 to 2 (1.30)

0.93

Ly18

15% to 40%

901

5

9

14

1 (0.95)

0.95

Jurkat

46.7% to 73.9%

792

2

3

4

1 (0.83)

0.98

  1. range: range of fractions for the cell type in the mixtures. markers: number of markers defined as positives from the analysis of the pure samples and present at least in one of the mixtures; top5 (10, 20): number of positive markers (see Methods) among the 5 (10, 20) most correlated probesets; expected top20: expected numbers of markers if we randomly selected 20 probesets; correlation of 20th: value of the correlation coefficient for the 20th most correlated probe set.